October in Cusco is the warmest month of the year. In October, the weather in Cusco is typically warm. Average daily high temperature in October is about 15 degrees above zero. On average, Cusco has 22 rainy, 5 cloudy, 3 partly cloudy, and 1 sunny day in October. The rains are usually heavy. October as well as January, February, March, and April is considered the most uncomfortable time to visit Cusco.