October in Murrells Inlet is the sunniest month of the year. In October, the weather in Murrells Inlet is typically warm. Average daily high temperature in October is about 22 degrees above zero. On average, Murrells Inlet has 20 sunny, 6 partly cloudy, and 5 rainy days in October. The rains are usually heavy. October as well as {{month_nom: February}}, and {{month_nom: February}} is considered the most comfortable time to visit Murrells Inlet.