October in Panacea is the sunniest month of the year. In October, the weather in Panacea is typically warm. Average daily high temperature in October is about 25 degrees above zero. On average, Panacea has 21 sunny, 5 rainy, and 5 partly cloudy days in October. The rains are usually moderate. October as well as April and November is considered the most comfortable time to visit Panacea.