In October, the weather in Puerto Maldonado is typically hot. Average daily high temperature in October is about 31 degrees above zero. On average, Puerto Maldonado has 25 rainy, 4 sunny, 1 cloudy, and 1 partly cloudy day in October. The rains are usually heavy. October as well as January, February, March, and April is considered the most uncomfortable time to visit Puerto Maldonado.