January in Santa Cruz de la Sierra is the rainiest and the cloudiest month of the year. In January, the weather in Santa Cruz de la Sierra is typically hot. Average daily high temperature in January is about 30 degrees above zero. On average, Santa Cruz de la Sierra has 25 rainy, 3 sunny, and 3 cloudy days in January. The rains are usually heavy. January as well as February and December is considered the most uncomfortable time to visit Santa Cruz de la Sierra.