In May, the weather in Santa Cruz del Quiché is typically warm. Average daily high temperature in May is about 19 degrees above zero. On average, Santa Cruz del Quiché has 29 rainy, 1 sunny, and 1 cloudy day in May. The rains are usually heavy. May as well as June, July, August, and September is considered the most uncomfortable time to visit Santa Cruz del Quiché.