In October, the weather in Santiago de los Caballeros is typically hot. Average daily high temperature in October is about 31 degrees above zero. On average, Santiago de los Caballeros has 16 rainy, 8 sunny, 4 partly cloudy, and 3 cloudy days in October. The rains are usually heavy. October as well as April, May, June, and July is considered the most uncomfortable time to visit Santiago de los Caballeros.