October in Tupelo is the sunniest month of the year. In October, the weather in Tupelo is typically warm. Average daily high temperature in October is about 22 degrees above zero. On average, Tupelo has 22 sunny, 5 rainy, and 4 partly cloudy days in October. The rains are usually moderate. October as well as {{month_nom: February}}, and {{month_nom: February}} is considered the most comfortable time to visit Tupelo.